AMERICA’S #1 PRESCRIBED BRANDED
HYPOTHYROIDISM MEDICATION1,2*

SYNTHROID has been committed to treating hypothyroidism for 65 years.3

  • Millions of patients manage their hypothyroidism with SYNTHROID1†

 

*2014-2020.
†2020.

SYNTHROID has been committed to treating hypothyroidism for 65 years.3

  • Millions of patients manage their hypothyroidism with SYNTHROID 1†

*2014-2020.
†2020.

SYNTHROID has been committed to treating hypothyroidism for 65 years.3

  • Millions of patients manage their hypothyroidism with SYNTHROID1†

 

*2014-2020.
†2020.

ABBVIE IS COMMITTED TO
MANUFACTURING INTEGRITY

In August 2002, the FDA released the Current Good Manufacturing Practices (CGMP) initiative to ensure the quality of drug products. The initiative contains minimum requirements for the methods, facilities, and controls used in manufacturing, processing, and packing of a drug product. These regulations make sure that a product is safe for use, and that it has the ingredients and strength it claims to have.4,5

AbbVie is committed to adhering to the CGMP and believes in the integrity of its manufacturing process. AbbVie is dedicated to ensuring that all SYNTHROID products are manufactured at the highest standards.

Note that FDA regulations require that all pharmaceutical manufacturers like AbbVie abide by CGMP.

SYNTHROID contains no ingredients made from a
gluten-containing grain (wheat, barley, or rye).2

ARE PATIENTS GETTING SYNTHROID
AS YOU PRESCRIBED?

32% of patients who think they
are taking SYNTHROID actually are not6*

Mistaken generic users defined as those who reported taking SYNTHROID but did not have “SYNTHROID” embossed on the pill in a national online survey conducted in 2021 of 1908 adults diagnosed with hypothyroidism and currently taking LT4  products.

That’s because substitutions can be made at the pharmacy if the prescription is not properly protected with the Dispense as Written (DAW) state-specific language.

The FDA has determined that certain levothyroxine products are interchangeable. The FDA has determined that drugs that are classified as therapeutically equivalent can be substituted with the full expectation that the substituted product will produce the same clinical effect and safety profile as the reference product.8

When prescribing SYNTHROID, include your DAW state-specific language to prevent generic substitution

PREVENTING NONMEDICAL
SUBSTITUTION AT THE PHARMACY

DAW codes are codes a pharmacy uses when filling your patient’s prescription. DAW-1 indicates that substitution is not allowed, based on the prescriber’s preference, and ensures your patient will receive the treatment you prescribe. It also helps your patient pay the lowest possible price for the product you write if it is billed through insurance.

When prescribing SYNTHROID, protecting your script can ensure your patients receive SYNTHROID every time they refill their prescription.

Dispense as Written (DAW); Synthroid refills

Tablets shown not actual size and may not represent exact color.

Synthroid Patient 1

Consider the following when switching from SYNTHROID

  • Most, but not all, levothyroxine products have been determined to be therapeutically equivalent by the FDA8
  • A levothyroxine product that is not therapeutically equivalent to SYNTHROID might not have the exact same effect on a patient’s TSH levels as SYNTHROID9
  • Switching between nontherapeutically equivalent levothyroxine treatments may lead to9:

    — More frequent patient visits

    — Additional laboratory tests

  • All hypothyroidism patients, including those remaining on consistent therapy, should have their TSH tested on a regular basis as recommended by their doctor2

SYNTHROID has 12 precise dosing options2   

USE YOUR STATE’S REQUIRED LANGUAGE
TO INDICATE A PRESCRIPTION IS DAW-1

Language needed to prevent generic substitution varies by state.

Use the drop-down menu below to select your state and see the specific language required to prevent generic substitution.10

Updated as of 11/15/2022. This state-specific information is Intended as guidance and suggestions only. This slide does not constitute legal advice and AbbVie is not responsible for providing updates or corrections. Please consult your local authority regarding state specific pharmacy regulations.

Language needed to prevent generic substitution varies by state.

Use the drop-down menu below to select your state and see the specific language required to prevent generic substitution.